Arsenic

Summary and recommendations for further research

Summary

Properties and analytical procedures

Environmental transport and distribution

Exposure

Metabolism

Normal levels in man and biological indicators of exposure

Effects and evaluation of health risks

Recommendations for further studies

Properties and analytical procedures

Chemical and physical properties of arsenic compounds

Analytical procedures

Analytical methods

Sources and occurrence of arsenic in the environment

Natural occurrence

Industrial production and uses of arsenic

Environmental transport and distribution

General

Aquatic systems

Air-soil systems

Levels of exposure to arsenic and its compounds

General population exposure through air, drinking water, food, and beverages

Metabolism of arsenic

Inorganic arsenic

Absorption

Distribution in organisms

Elimination

Biotransformation

Organic arsenic compounds

Absorption

Distribution in organisms

Elimination

Biotransformation

Normal levels in man biological indicators of exposure

Blood

Urine

Hair

Other tissues

Effects and dose-response relationships of organic arsenic

Acute and subacute effects after short-term exposure

Effects on reproduction and teratogenicity

Noncarcinogenic effects after long-term exposure and sequelae of short-term exposure to organic arsenic

Carcinogenicity

Mutagenicity

Mechanisms of toxicity

Effects and dose-response relationships of organic arsenic compounds

Acute and chronic toxicity

Teratogenicity

Carcinogenicity

Mutagenicity

Mechanisms of toxicity

Interactions with other chemicals

Thiol-compounds

Selenium

Cadmium and lead

Evaluation of health risks to man from exposure to arsenic

Exposure

Inorganic arsenic compounds

Organic arsenic compounds

Assessment of the cancer risk for man from exposure to inorganic arsenic

Inglés