Tetrabromobisphenol A and derivatives

Summary and evaluation

Physical and chemical properties

Production and use

Environmental transport, distribution and transformation

Environmental levels and human exposure

Kinetics and metabolism in laboratory animals and humans

Effects on laboratory mammals, and in vitro test systems

Effects on other organisms in the laboratory and field

Conclusions

Recommendations

Identity, physical and chemical properties, analytical methods

Identity

Physical and chemical properties

Conversion factor for air concentrations

Analytical methods

Sources of human and environmental exposure

Natural occurrence

Anthropogenic sources

Environmental transport, distribution and transformation

Transport and distribution between media

Transformation

Interaction with other physical, chemical, and biological factors

Ultimate fate following use

Environmental levels and human exposure

Environmental levels

General population exposure

Occupational exposure

Kinetics and metabolism in laboratory animals and humans

Absorption and elimination

Metabolism

Effects on laboratory mammals, and in vitro test systems

Single exposure

Short-term exposures

Long-term exposure

Skin and eye irritation; sensitization

Reproductive toxicity, embryotoxicity and teratogenicity

Mutagenicity and related end-points

Carcinogenicity

Other special studies

Effects on human

Effects on other organisms in the laboratory and field

Laboratory studies

Field observations

Miscellaneous

Inglés